ERRFI1 antibody

Catalog No. ABIN7465778

This anti-ERRFI1 antibody is a Rabbit Polyclonal antibody detecting ERRFI1 in WB and IHC (p). Suitable for Human.

Quick Overview for ERRFI1 antibody (ABIN7465778)

Target: ERRFI1 (ERBB Receptor Feedback Inhibitor 1 (ERRFI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERRFI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ERRFI1 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Mig-6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.29 mg/mL

Buffer: 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ERRFI1

Target: ERRFI1 (ERBB Receptor Feedback Inhibitor 1 (ERRFI1))

Alternative Name: ERBB receptor feedback inhibitor 1

Background: ERBB receptor feedback inhibitor 1 , GENE-33 , MIG-6 , MIG6 , RALT,ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885], Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM]

Molecular Weight: 51 kDa

Gene ID: 54206

UniProt: Q9UJM3

Pathways: EGFR Signaling Pathway